J & J’s Booster Brings Robust Protection Against Omicron, Study Shows

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News Picture: J & J's Booster Brings Robust Protection Against Omicron, Study ShowsBy Ernie Mundell HealthDay Reporter

THURSDAY, Dec. 30, 2021 (HealthDay Information)

New information out of South Africa finds {that a} booster dose of Johnson & Johnson’s COVID-19 vaccine seems to offer sturdy safety in opposition to extreme illness attributable to the fast-spreading Omicron variant.

The study, which was revealed on-line and has not but undergone peer assessment, was carried out in a bunch of greater than 69,000 South African well being care staff. All of them acquired their boosters six to 9 months after having already acquired one dose of the J & J vaccine.

The boosted well being staff’ outcomes have been in comparison with an analogous variety of unvaccinated South Africans.

The examine discovered that individuals who’d gotten the J & J booster shot have been 85% much less more likely to require hospitalization attributable to an an infection from Omicron, in comparison with unvaccinated individuals.

That compares effectively to other data from South Africa exhibiting {that a} booster shot of the two-dose Pfizer vaccine lower the chance of hospitalization by 70%.

The brand new information flies within the face of current suggestions from the U.S. Facilities for Illness Management and Prevention. The CDC continues to be authorizing use of the J & J vaccine, however is recommending that other vaccines, such because the Pfizer or Moderna pictures, be most popular as boosters. The company primarily based its advice on a raised threat of very uncommon however probably life-threatening blood clots tied to make use of of the J & J vaccine.

In a separate U.S. arm of a trial that wrapped up in September — when the Delta variant was nonetheless dominating — Johnson & Johnson found that giving individuals a second dose of the vaccine two months after they’d acquired their first brought about safety from COVID-linked hospitalization to rise from 74% earlier than the booster to 94% after. Comparable outcomes have been seen in trials throughout 10 nations.

Whereas the big majority of vaccinated People have acquired both the Pfizer or Moderna mRNA vaccines, populations in Africa and elsewhere have usually relied on the one-dose Johnson & Johnson shot. So, the brand new findings could possibly be an actual boon to individuals in growing nations, consultants consider.

The brand new South African findings on J & J boosters come as considerably of a shock, since laboratory experiments discovered the pictures had little effectiveness in opposition to the extremely mutated Omicron variant. Nonetheless, consultants consider the booster may increase ranges of antibodies to strong ranges, or may match on different gamers within the human immune system to assist combat off the variant.

Extra info:

There’s extra on the Omicron variant of the brand new coronavirus on the CDC.

SOURCES: medRxiv, on-line publication, Dec. 29, 2021

MedicalNews

Copyright © 2021 HealthDay. All rights reserved.



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